· an event in which one thing is substituted for another; "the replacement of lost blood by a transfusion of donor blood"
Synonym(s): permutation, transposition, replacement, switch
Hypernym(s): variation, fluctuation
· the act of putting one thing or person in the place of another: "he sent Smith in for Jones but the substitution came too late to help"
Synonym(s): exchange, commutation
Hypernym(s): change